GHK WITH COPD

This information is for the use of medical researchers and persons interested in health sciences. It must be emphasized that GHK and other copper binding peptides have not been tested on human emphysema and COPD and are not approved for such uses.

 

Emphysema and attendant lung disease is the 2rd leading cause of death in the world. It is a deadly and painful disease of the lungs that causes difficulty in breathing. In people with emphysema, the tissues necessary to support the physical shape and function of the lungs are destroyed. Emphysema is most often caused by tobacco smoking and long-term exposure to air pollution. Emphysema is also a component of normal aging. As the lungs get older, the elastic properties decrease, and the tensions that develop can result in areas of emphysema.

 

In the study below, it was found that GHK, at a very low concentration (10 nanomolar) reversed the effects of emphysema on the genes of affected fibroblast cells from the patients. GHK shut down tissue destructive genes and increased genes that control wound repair and tissue remodeling.

 

Persons with severe emphysema use air inhalation systems that pump misty, water-filled air in and out of the lungs. Often steroids are added to the solution to suppress the lung inflammation, but while this provides short-term help, it also inhibits lung repair. In theory, GHK could be infused into the blood stream of patients to repair the lung tissue. In our wound healing studies we found that GHK-copper induced accelerated systemic healing through rats, mice , and pigs. Or it could be added to the misting solution or used in combination of a carrier like DMSO along with GHK in the misting solution. DMSO and GHK or GHK-copper always worked well together on wound healing.

 

The full article is available at no cost at www.genomemedicine.com/content/4/8/67.

Original Post

 "In the study below, it was found that GHK, at a very low concentration (10 nanomolar) reversed the effects of emphysema on the genes of affected fibroblast cells from the patients."

          *** *** ***

Wow!  Is the FDA aware of this?  If so, why haven't they approved it and allow it to start being used to help patients?  COPD is 24/7 suffering from not being able to get enough oxygen to the brain.  A walk to the bathroom becomes a major event.  Talking after the slightest exertion is impossible!  It is a life of pure hell and it lasts a long time before it finally releases you to the Grim Reaper.  So much suffering and there is a way that is clearly known to help and even alleviate  it yet the FDA hasn't approved it to be used for patients who are in need of it?

Is this another issue like the medical marijuana one?  Scientists have known for years of the potential of medical marijuana and yet the government halted  scientific research for decades and decades, and refused to allow it to be researched and experimented with legally until this sudden recent flurry of interest that seems to be happening lately (more than likely due to the fact that our country needs the money)!  It is now known that cannabis can cure certain forms of cancer with the oil and yet even now, with articles by doctors and scientists who have proven this, it still remains illegal in most places.

Copper Peptides, medical marijuana, both radically capable of doing miraculous things for the body to heal it and improve quality of life while alleviating much of the suffering.  They have known it for some time and yet they still hold it back away from its citizens!

How many years has it been since the power of what copper can do for COPD patients has been known?  And it is known now and yet now being used.  Think of how many patients suffering from COPD could be helped tremendously with this.  When one can no longer get a breath of air to walk across the room without gasping for oxygen, the  quality of life continues to diminish until it barely seems worth staying alive to just continue to get worse and worse until even turning over in bed becomes too difficult because one cannot get enough air to preform this simple task!
I find it extremely upsetting that people are left to suffer when known cures are available but are being held back from the people who need them the most and whose lives are ruined while living in chronic pain and suffering that could be alleviated,

I took care of my mother for the last 10 years of her life as she slowly wasted away from COPD.  I watched as she went from a health, vibrant woman to a near skeleton  who could barley get around her one floor condo and later became bedridden in a nursing unable to turn herself in bed without help, constantly begging the nurses to turn up the oxygen as she felt like she couldn't breath.  I watched as gradually her brain functioning diminished and she developed Altzhimer's or some kind of senile dementia   most likely due to the lack of oxygen.  They used to find her at night getting out of bed and turning up the oxygen machine she was on and they would yell at her gut all she as trying to do was get a few real breaths of air!
Ten years of living hell before she was released from the suffering - and this body of knowledge now tells me that if copper had be allowed to be used for medical purposes like COPD those 10 years would have been very different for her with less or no suffering, no nursing home or oxygen needed and a longer happier life!

Today we hear stories of children an adults with epilepsy, cancer  and other disorders who are suffering and dying needlessly because they are unable to get the medicine they need due to prohibition; and we have discovered that the government has known about these capabilities all this time but chose to prohibit a medication that used to be on every pharmacy's shelf decades ago.

Both my mother's life and mine would have been radically different if she had been allowed to have copper peptides when she was in such deep suffering and gasping for air.  Who knows she might have lived many years longer and had a much better quality of life if they had used copper to help her as opposed to the standard copd medicines which seemed to do nothing at all!


GHK has a potential for treating several diseases and in all the research on the molecule, no negative actions have ever been reported.  But I doubt if it will ever used in the USA because of its low cost. Think of the new $1,000 a day drug for the treatment of hepatitis C of the liver. The best possibility is that it be used as a nutritional supplement and encapsulated in liposomes for oral use. It should fit the legal definition of a nutritional supplement.

 

But GHK may be used in countries where the is less control by large corporations and much lower drug costs.

 

There is huge hostility to this work, even though results have been reported from about 100 laboratories, from the US government and many academic researchers. I really don't know why, I think at times that they want all of us to die in pain, misery, and poverty.

Originally Posted by Bart:

Does anyone know if GHK is available orally as a supplement?  from other countries maybe?

 

thanks!

Liposomal GHK and GHK-copper2+ are sold.

 

Glycyl-L-Histidyl-L-Liysine-Cu(2+) loaded liposome formulations

AUTHOR(S)
Erdem, Setenay; T�rko�lu, Murat
PUB. DATE
May 2010
SOURCE
Marmara Pharmaceutical Journal;May2010, Vol. 14 Issue 2, p91
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Enhancement of collagen synthesis by glycyl-l-histidyl-l-lysine-Cu2+ (GHK-Cu) derivatives is well known. The different activities of GHK-Cu would be of interest for cosmetic applications. Liposomes provide many benefits as topical drug delivery systems. Structure of double layer and lipid composition of liposomes keep the active substance longer in skin and provide regularly release to the deeper skin layers. Our aim in this study was to prepare GHK-Cu loaded liposomes and characterize them to use in a cosmetic formulation. UV spectrophotometric method was used to detect the GHK-Cu in aqueous medium and FTIR spectrums were taken to determine the absorption bands. In stability studies, it was observed that aqueous solutions of GHK-Cu samples maintained their stability at 4�C for 4 months and the FTIR absorption bands of powdered GHK-Cu did not change when stored under the same stability conditions with aqueous samples. Different liposome formulations were prepared by lipid film hydration technique using different kinds of phospholipids (dipalmitoylphosphatidylcholine (DPPC-5911), Epicuron 100H, and Epicuron 200SH). The particle size and shape of liposomes were determined using microscope, SEM, and laser diffraction method. The average particle size was found to be 13�m. In the percent entrapment studies of GHK-Cu in liposomes, it was found that the highest entrapment was achieved with the liposomes prepared with Epicuron 100H. It was concluded that diffusion of GHK-Cu from liposomes prepared with Epicuron 100H was higher and more steady than that of liposomes prepared with DPPC and Epicuron 200SH in diffusion studies where a dialysis tubing was used.

 

 

 

http://connection.ebscohost.co...-histidyl-l-liysine-

cu-2-loaded-liposome-formulations

 

http://madeinchina.tradekey.com/liposome-ghk-cu.htm

My brother just had two heart attacks. After being brought back from the dead twice he found out, during a checkup, that he also has COPD. Like your mom, he is steadily in decline, probably more emotionally and psychologically b/c he really has no hope from his doctors that there is anything that can be done.  
 
I am never surprised but always amazed what the supposedly Health Care System is (not) doing for the health of humanity.  We know that a cure for cancer was found and used for stage 4 patients in a 3-week time period.  The scientist that discovered and experimented with success
got notice from "them" to stop all research or his home and family would be taken.
 
Medical marijuana: Totally amazing to me how the "herbs of healing" are also banned. 
 
I, like you, believe the humanity has suffered great injustices for what our "care takers" have failed to offer to the sick and dying.
 
 

 "In the study below, it was found that GHK, at a very low concentration (10 nanomolar) reversed the effects of emphysema on the genes of affected fibroblast cells from the patients."

          *** *** ***

Wow!  Is the FDA aware of this?  If so, why haven't they approved it and allow it to start being used to help patients?  COPD is 24/7 suffering from not being able to get enough oxygen to the brain.  A walk to the bathroom becomes a major event.  Talking after the slightest exertion is impossible!  It is a life of pure hell and it lasts a long time before it finally releases you to the Grim Reaper.  So much suffering and there is a way that is clearly known to help and even alleviate  it yet the FDA hasn't approved it to be used for patients who are in need of it?

Is this another issue like the medical marijuana one?  Scientists have known for years of the potential of medical marijuana and yet the government halted  scientific research for decades and decades, and refused to allow it to be researched and experimented with legally until this sudden recent flurry of interest that seems to be happening lately (more than likely due to the fact that our country needs the money)!  It is now known that cannabis can cure certain forms of cancer with the oil and yet even now, with articles by doctors and scientists who have proven this, it still remains illegal in most places.

Copper Peptides, medical marijuana, both radically capable of doing miraculous things for the body to heal it and improve quality of life while alleviating much of the suffering.  They have known it for some time and yet they still hold it back away from its citizens!

How many years has it been since the power of what copper can do for COPD patients has been known?  And it is known now and yet now being used.  Think of how many patients suffering from COPD could be helped tremendously with this.  When one can no longer get a breath of air to walk across the room without gasping for oxygen, the  quality of life continues to diminish until it barely seems worth staying alive to just continue to get worse and worse until even turning over in bed becomes too difficult because one cannot get enough air to preform this simple task!
I find it extremely upsetting that people are left to suffer when known cures are available but are being held back from the people who need them the most and whose lives are ruined while living in chronic pain and suffering that could be alleviated,

I took care of my mother for the last 10 years of her life as she slowly wasted away from COPD.  I watched as she went from a health, vibrant woman to a near skeleton  who could barley get around her one floor condo and later became bedridden in a nursing unable to turn herself in bed without help, constantly begging the nurses to turn up the oxygen as she felt like she couldn't breath.  I watched as gradually her brain functioning diminished and she developed Altzhimer's or some kind of senile dementia   most likely due to the lack of oxygen.  They used to find her at night getting out of bed and turning up the oxygen machine she was on and they would yell at her gut all she as trying to do was get a few real breaths of air!
Ten years of living hell before she was released from the suffering - and this body of knowledge now tells me that if copper had be allowed to be used for medical purposes like COPD those 10 years would have been very different for her with less or no suffering, no nursing home or oxygen needed and a longer happier life!

Today we hear stories of children an adults with epilepsy, cancer  and other disorders who are suffering and dying needlessly because they are unable to get the medicine they need due to prohibition; and we have discovered that the government has known about these capabilities all this time but chose to prohibit a medication that used to be on every pharmacy's shelf decades ago.

Both my mother's life and mine would have been radically different if she had been allowed to have copper peptides when she was in such deep suffering and gasping for air.  Who knows she might have lived many years longer and had a much better quality of life if they had used copper to help her as opposed to the standard copd medicines which seemed to do nothing at all!


 

This information is for the use of medical researchers and persons interested in health sciences. It must be emphasized that GHK and other copper binding peptides have not been tested on human emphysema and COPD and are not approved for such uses.

 

One way that may help with COPD is to take 6 mg/day of copper glycinate after a meal. 

Look at the new revision of 

http://www.skinbiology.com/cop...sema-copd-genes.html

for the reasons behind this idea. It may not stop COPD but it may help to minimize its effects. Clear this with your physician before doing this, since I am not a physician. 

Thank you for your quick response. You are a great man doing a great work. Like many great men/women before you there is one caveat to greatness; and that is you/they are many years ahead of the time. I appreciate your advancement(s) in this area of science and research.

This is actually an ultrasonic cool mist inhaler... Ultrasonic wave puts the liquid medication ( reconstitute the Peptide GHK-cu with Bacteriostatic water) into an ultra fine mist. 

I know the advertising says Steam but its not... the manufacturer from China just doesn't know how to describe the product correctly in English.  Trust me it works by ultrasonic wave.

Search for Magicfly on Ebay...  it's so cheap but works so well... instantly creates a mist...

Don't buy GHK-cu POWDER that is used for cosmetics to put in creams as you can't trust something like that to be pure and certainly isn't sterile...  you must use  GHK-cu Peptide which will come in a sterile vacuum sealed vial and the peptide is Lyophilized which means its freeze dried and will look like a white disc... 

 

Search for Research peptides

 

Peptide Sciences   and others

Please let me know if you hear of any good results with this system. My hope is that physicians outside of the USA start testing GHK-copper on patients. My fear is that the big pharma will replace GHK with an expensive synthetic drug filled with side effects. The person's lungs might work better, but their hair will fall out, they will have constant nausea, and their cognitive ability will plummet. 

Dr I sure will report back here...people need to know .

There is a lot of research on GHK and I haven't read one negative to using it. It's use can go well beyond COPD's use...  Dr's need to band together to use natural peptides like GHK to heal people.  It's naturally occurring so they have a lot of leeway in it's use... If anything GHK declines with age and should be used to bring the levels back to a more normal state to facilitate normal healthy healing.  Big pharma will want to alter it to patent it and in doing so do a lot of harm.  To me GHK looks like a miracle peptide that could save a lot of lives and make life more enjoyable for many people again.

 

Dr. Pickart,

     My name is Mike Smalling, and I’m currently a grad student at Louisiana Tech University studying in molecular science. I have read many of your papers, and became very interested in the tripeptide GHK through them. I have also read Dr. Campbell’s work on COPD, and Dr. Lane’s work with SPARC as well as others. I intended to do a master’s thesis on research of the tripeptide, but after I had gotten through the initial research, my advisors here realized I was in an area they were totally unfamiliar with and uncomfortable with me pursuing that line. However, I am still very interested, and believe there is a great deal more to GHK than has been researched. My initial research in silico gave results in proteins which may be known, but I haven’t found it published. Do you known if the mechanism of action has been researched on the tripeptide? Or if the tripeptide passes the BBB? I can find no information on this.

     It doesn’t appear that I will be able to pursue research on this line anytime soon here, but if you are continuing research on the tripeptide perhaps you could use the information I’ve found. I believe the tripeptide could be an important therapeutic in several areas and believe someone should pursue this if possible. I would appreciate any information you might be able to share with me, and would be glad to give you my information as well, such as it is. The best way to contact me is at my school address mds070@latech.edu. I hope to hear from you.

Sincerely,

Mike Smalling

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