EXCERPT: "Treatment of human fibroblasts with GHK recapitulated TGFβ-induced gene-expression patterns, led to the organization of the actin cytoskeleton, and elevated the expression of integrin β1. Furthermore, addition of GHK or TGFβ restored collagen I contraction and remodeling by fibroblasts derived from COPD lungs compared to fibroblasts from former smokers without COPD...
Furthermore, [it was shown] that by treating distal lung fibroblasts from COPD patients with GHK, we can restore normal contractile function through re-organization of the actin cytoskeleton and up-regulation of integrin-β1. These data further support the potential of GHK as a therapeutic in the treatment of emphysema."
Read the full article at: https://genomemedicine.biomedc...ticles/10.1186/gm367
Biochemist (and discoverer of GHK) Dr. Loren Pickart, provides further information, comments, and ideas at: http://www.skinbiology.com/cop...sema-copd-genes.html