Tagged With "GHK-copper"

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GHK's Role in Novel Therapeutics for Emphysema

Skin Biology ·
Novel Therapeutics for Emphysema We have followed with great interest recent data on gene expression signature of emphysema-related lung destruction and its reversal by the tripeptide GHK - Genome Medicine CLICK HERE Excerpt: "As the CMap examined the effect of GHK in cancer cell lines, we next sought to verify the effect of GHK treatment in a cell type more relevant to emphysema pathogenesis. We utilized human lung fibroblasts because fibroblasts are the major interstitial cell within the...
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Why It Should Matter to You: GHK Reverses Cortisone Inhibition of Regeneration

Skin Biology ·
GHK Reverses Cortisone Inhibition of Regeneration - Why It Should Matter to You NEW PAGE! - CLICK HERE: www.reverseagingwithghk.com/ghk-reverses-cortisone-inhibition-of-regeneration.html Cortisone and cortisol are linked to brain problems and dementia. These two very similar molecules are easily converted from one to another.Patients with Alzheimer’s disease have elevated levels of cortisol in their blood streams, compared to healthy patients. This elevation correlated with the degree of...
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GHK & Wound Healing: Built-In Natural Regulator of Dermal Repair

Skin Biology ·
GHK & Wound Healing: Built-In Natural Regulator of Dermal Repair The wound healing process in the skin goes through the following phases: hemostasis (blood clotting), inflammation, granulation, and scar remodeling. Every stage requires well-coordinated cell interaction and therefore is precisely orchestrated by a plethora of biological active molecules coming from different sources. For example, immediately after injury degranulating platelets release growth factors (such as TGF-beta)...
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IMPORTANT NEWS! GHK-Cu Study on Acute Lung Injury

Skin Biology ·
Oncotarget. 2016 Aug 10 . doi: 10.18632/oncotarget.11168. [Epub ahead of print] The tri-peptide GHK -Cu complex ameliorates lipopolysaccharide-induced acute lung injury in mice. Park JR 1, 2 , Lee H 1 , Kim SI 3 , Yang SR 1 . Author information Abstract The tripeptide-copper complex glycyl-l-histidyl-l-lysine-Cu (II) ( GHK -Cu) is involved in wound healing and tissue remodeling. Although GHK -Cu exhibits anti-aging and tissue renewing properties, its roles in acute lung injury (ALI)/acute...
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GHK - Now Part of Major Reference Textbook on Skin!

Skin Biology ·
Resetting Skin Genome Back to Health Naturally with GHK Textbook of Aging Skin (Reference Book Abstract) The copper-binding tripeptide GHK (glycyl- l -histidyl- l -lysine) is a naturally occurring plasma peptide widely used in skin care products. It is especially popular in antiaging cosmetic formulations due to its various and well-established positive biological effects on aging skin. It has been established that GHK-Cu improves wound healing and tissue regeneration and stimulates collagen...
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Visual Presentation of Cancer Metastasis Genetic Data

Skin Biology ·
Visual Presentation of Cancer Metastasis Genetic Data and GHK VISIT: www.skinbiology.com/wound-healing-society-2011.htm Dr. Loren Pickart presented the following visual at the Society for the Advancement of Wound Care and the Wound Healing Society in Dallas, Texas. The presentation focused on data confirming that GHK may inhibit cancer genes, suggesting a connection between metastatic cancer cells and similar systems utilized in the early stage of wound healing.
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CLINICAL STUDY: Copper Peptides vs. Retinoid Acid and Vitamin C Topical

Skin Biology ·
Copper Peptides vs. Retinoid Acid and Vitamin C A MUST READ: www.skinbio.com/copper-peptides-aging-reversal-studies.php Human Skin Renewal Study : A clinical study which compared the effect on the skin's production of collagen after using creams containing copper-peptides, vitamin C, or retinoic acid (retin-A). Twenty volunteers applied the various creams to their thighs daily for one month. New collagen production was determined by studying skin biopsy samples using immunohistological...
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DMSO + GHK: An Amazingly Effective Combination

Skin Biology ·
Skin and Hair Transplantation GHK-Cu substantially improved the transplants of skin grafts in pigs, mice, and humans. The best results were obtained by using GHK-Cu dissolved in a small amount of DMSO (dimethylsulfoxide). Normally in skin grafts, most of the grafted skin dies off, and new skin grows outward from the surviving core of the skin graft. However, the addition of DMSO often so improved the graft "take" that the final graft "take" area exceeded the actual size of the skin graft.
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RIVER OF LIFE: Human Aging Explained Visually

Skin Biology ·
River of Life & Human Aging A MUST SEE: www.skinbiology.com/RiverofLife_AgingTheory.pdf Dr. Pickart renowned biochemist and advent of aging prevention visually explains the effects of human aging. Like a river, human genes start out wide, in tune, and healthy. But gradually health narrows and can lead to abnormal growths and/or senescence. Learn more at: www.skinbiology.com/RiverofLife_AgingTheory.pdf What is truly being done to slow down the effects of human aging? Visit Reverse Aging...
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ANNOUNCEMENT: New Article Published on GHK & Nerve Function - A Must Read

Skin Biology ·
The Effect of GHK on Nervous System Function and Cognitive Decline NEW ARTICLE PUBLISHED!! Why is this so important? A ge-related cognitive decline is a common problem for many elderly people, yet its cause is poorly understood. Over 99% of investigational drugs, participating in over 200 clinical trials, failed to receive approval for the treatment of Alzheimer’s disease [ 1 ]. Even the success of a few approved drugs provides only minimal patient improvement. There is a need for new, safe,...
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NEW! Brain Sciences Tweet About GHK Research!

Skin Biology ·
The Effect of the Human Peptide GHK on Gene Expression Relevant to Nervous System Function and Cognitive Decline Dr. Loren Pickart's paper on GHK and neurodegeneration (the progressive death of neurons, loss of brain function, and cognitive decline which is an increasing problem for senior populations) has just been approved by Brain Sciences Journal! Like and Follow: https://twitter.com/BrainSci_MDPI/status/831789711022780418
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Genetic Piano Keys? Could GHK Be the Answer to Retuning You Back to Health?

Skin Biology ·
The Piano Key Theory of Human Aging The main cause of human aging appears to be that the genes lose their optimal pattern of UP and DOWN settings (age 20-25). This is like piano keys. When the piano is new, it plays beautiful music, but with time the piano keys lose their proper tuning as the music is imperfect. Likewise, with time human genes lose their youthful settings and the diseases and conditions of aging set in. GHK, which was discovered during biochemical studies of human aging,...
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NEW BOOK RELEASE! and Why It Is Important

Skin Biology ·
NEW RELEASE - Order here: https://www.createspace.com/7352739 GHK-Copper Peptides for Skin and Hair Beauty Why is this publication is important? Includes never-before released data on cancer, COPD, anti-pain, and anti-anxiety effects of GHK. COPPER PEPTIDES RETUNE YOUR GENE PIANO TO HEALTH - However, not all copper peptides improve skin or hair. Learn from the discoverer of regenerative copper peptides, biochemist Dr. Loren Pickart, the secrets that have most recently been revealed about...
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Book Release: How to Get Your Copy

Skin Biology ·
NEW RELEASE - Order here: https://www.createspace.com/7352739 GHK-Copper Peptides for Skin and Hair Beauty Why is this publication is important? Includes never-before released data on cancer, COPD, anti-pain, and anti-anxiety effects of GHK. COPPER PEPTIDES RETUNE YOUR GENE PIANO TO HEALTH - However, not all copper peptides improve skin or hair. Learn from the discoverer of regenerative copper peptides, biochemist Dr. Loren Pickart, the secrets that have most recently been revealed about...
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It's FINISHED! Why My New Book is My Proud Accomplishment

Skin Biology ·
NEW RELEASE - Order here: https://www.createspace.com/7352739 GHK-Copper Peptides for Skin and Hair Beauty Why is this publication is important? Includes never-before released data on cancer, COPD, anti-pain, and anti-anxiety effects of GHK. COPPER PEPTIDES RETUNE YOUR GENE PIANO TO HEALTH - However, not all copper peptides improve skin or hair. Learn from the discoverer of regenerative copper peptides, biochemist Dr. Loren Pickart, the secrets that have most recently been revealed about...
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NEW Book on Cancer Research and Gene Data

Skin Biology ·
NEW RELEASE - Order here: https://www.createspace.com/7352739 GHK-Copper Peptides for Skin and Hair Beauty Why is this publication is important? Includes never-before released data on cancer, COPD, anti-pain, and anti-anxiety effects of GHK. COPPER PEPTIDES RETUNE YOUR GENE PIANO TO HEALTH - However, not all copper peptides improve skin or hair. Learn from the discoverer of regenerative copper peptides, biochemist Dr. Loren Pickart, the secrets that have most recently been revealed about...
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Reversal of Emphysema-Related Lung Destruction?

Skin Biology ·
Emphysema-Related Lung Destruction and its Reversal by GHK (Genome Medicine) EXCERPT: "Treatment of human fibroblasts with GHK recapitulated TGFβ-induced gene-expression patterns, led to the organization of the actin cytoskeleton, and elevated the expression of integrin β1. Furthermore, addition of GHK or TGFβ restored collagen I contraction and remodeling by fibroblasts derived from COPD lungs compared to fibroblasts from former smokers without COPD... Furthermore, [it was shown] that by...
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DMSO & GHK: A Success Story

Skin Biology ·
DMSO & GHK: A Success Story Background & Observations : GHK-Cu improved the skin transplants with the best results being obtained by using GHK-Cu dissolved in a small amount of DMSO (dimethylsulfoxide). Normally in skin grafts, most of the grafted skin dies off, and new skin grows outward from the surviving core of the skin graft. However, the addition of DMSO often so improved the graft "take" that the final graft "take" area exceeded the actual size of the skin graft. Periphery of...
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Anti-Cancer Properties of Copper Peptides (April 2018 Publication)

Skin Biology ·
Skin Regenerative and Anti-Cancer Actions of Copper Peptides (Cosmetics Magazine - April 21, 2018) The following paper was just released for public viewing - Within days of its release, this publication had over 300+ views and 130+ downloads | Read for yourself and your family: Dr. Pickart's NEW Article on Skin Regenerative and Anti-Cancer Actions of Copper Peptides - CLICK HERE Excerpt: " Peptides are widely popular cosmetic ingredients. They achieve instant improvement of skin’s appearance...
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Know Someone With Eczema? UPDATED Information Just for You

Skin Biology ·
The Challenge: Many so-called "anti-aging" creams contain detergents that cause swelling of the skin’s proteins, creating an immediate illusion of wrinkle reduction. But this swelling can further weaken the skin’s protective barrier, making eczema even worse. Exotic plants and new “miracle” ingredients that are foreign to your skin’s biology can further exacerbate eczema symptoms. Once the cause of irritation is found, you may need to find a product that can help with symptoms until the...
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NEW RELEASE: Actions of GHK in the Light of New Gene Data

Skin Biology ·
Protective Actions of GHK-Cu Peptide in the Light of NEW Gene Data (International Journal of Molecular Sciences - July 2018) The following paper was just released for public viewing: Dr. Pickart's NEW Article on Protective Actions of GHK-Cu Peptide - CLICK HERE Excerpt: " The human peptide GHK (glycyl- l -histidyl- l -lysine) has multiple biological actions, all of which, according to our current knowledge, appear to be health positive. It stimulates blood vessel and nerve outgrowth,...
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Why Following GHK-Cu Research Is VITAL

Skin Biology ·
Diseases of aging affect us all - B ased on laboratory data and gene profiling data, GHK-Cu may be used to improve stem cell therapy and to help shift regeneration processes of a number of organs back to healthy regeneration. Keep up-to-date with all of the recent studies, university and lab research, and potential uses of GHK-Cu ( glycine-L-histidine-lysine). Contact us at: ghkcopperpeptides@gmail.com for additional information READ MORE: Published Articles and Presentations - The Science...
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Breaking News: Strokes and GHK's Neuroprotective Effects

Skin Biology ·
Glycine-Histidine-Lysine (GHK) Alleviates Neuronal Apoptosis Due to Intracerebral Hemorrhage via the miR-339-5p/VEGFA Pathway (Frontiers in Neuroscience - September 2018) The following paper was just published this September | Read for yourself and your family: Glycine-Histidine-Lysine (GHK) Alleviates Neuronal Apoptosis Due to Intracerebral Hemorrhage via the miR-339-5p/VEGFA Pathway Excerpt: " Although it accounts for approximately 15% of all stroke cases, hemorrhagic stroke is associated...
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RUSSIAN Articles: Biological Mechanism of Action of GHK-Cu TriPeptide

Skin Biology ·
The primary cause of human aging and its attendant diseases are changes in the activity of the human genome. During aging there is an increase in the activity of inflammatory, cancer promoting, and tissue destructive genes plus a decrease in the activity of regenerative and reparative genes. Regenerative copper peptides appear to help maintain wellness and youth. The human peptide GHK induces a plethora of health associated actions such as tissue repair, anti-inflammatory actions,...
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(Russian Articles) - Is GHK the Secret to Unlock Human Aging?

Skin Biology ·
The primary cause of human aging and its attendant diseases are changes in the activity of the human genome. During aging there is an increase in the activity of inflammatory, cancer promoting, and tissue destructive genes plus a decrease in the activity of regenerative and reparative genes. Regenerative copper peptides appear to help maintain wellness and youth. The human peptide GHK induces a plethora of health associated actions such as tissue repair, anti-inflammatory actions,...
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Does Magnesium Citrate interfer with Copper Absorption?

Rossana ·
I would like to ask Skin Biology an opinion about Magnesium Citrate supplements. I have been taking Magnesium Citrate powder for years. It is the only magnesium form that I know of that is tasteless and I prefer powders to pills. I typically sprinkle 1 teaspoon of magnesium citrate on a meal, once or twice a day. 1 tsp = 3325 mg Magnesium Citrate = 540 mg elemental Magnesium. I recently read some references that magnesium, in the form of magnesium citrate, interferes with copper absorption...
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The ORIGINAL GHK Isolation Thesis! Now Public for You to View

Skin Biology ·
We have many people who ask about how Dr. Pickart originally isolated GHK and the inner workings of his unique discovery now being studied for its multiple, positive health applications around the world. CLICK HERE to read " A TriPeptide from Human Serum Which Enhances the Growth of Neoplastic Hepatocytes: How GHK was Isolated " (June 1973). 107 Pages of scientific biological discovery at its best!
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The Process of Isolating GHK: 1973 GHK Thesis NOW Online

Skin Biology ·
CLICK HERE to read " How GHK Was Isolated : A TriPeptide from Human Serum Which Enhances the Growth of Neoplastic Hepatocytes " (June 1973). 107 Pages of scientific biological discovery at its best! We have many people who ask about how Dr. Pickart originally isolated GHK and the inner workings of his unique discovery now being studied for its multiple, positive health applications around the world.
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Longer Telomeres Increase Cancer in Humans

Skin Biology ·
Longer Telomeres Increase Cancer in Humans (Important 22 Year Study) There is an idea that longer telomeres in humans will extend the lifespan. However, the following study of 28,000 people over 22 years found that those with the longest telomeres have much higher rates of cancer - CLICK HERE STUDY DETAILS: For the new study, researchers analyzed blood samples and health data on more than 28,000 Chinese people in the Singapore Chinese Health Study, which has followed the health outcomes of...
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IMPORTANT NEWS! GHK and Cancer Treatment

Skin Biology ·
MUST-READ! Peptides in Cancer Management: Interesting information on GHK-Cu GHK as approach for immediate clinical use. "Peptides, both endogenous and synthetic, play a role in both immune health and as complementary therapies in cancer treatment." https://agemed.org/wp-content/uploads/MARTINEZ-Peptides-for-Cancer.pdf
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Cancer Suppression with Vitamin C and Copper:Gly-Gly-His

Jessica ·
This information is for the use of medical researchers and persons interested in health sciences. It must be emphasized that GHK and other copper binding peptides have not been tested on human cancers and are not approved for such uses. In 1983...
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GHK Suppression of Cancer Metastasis Genes

Jessica ·
This information is for the use of medical researchers and persons interested in health sciences. It must be emphasized that GHK and other copper binding peptides have not been tested on human cancers and are not approved for such uses. In 2010,...
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Wound Healing & Skin Repair Using Copper Peptides

skinbiologywebmaster ·
 StudyResultReference US Patents describing methods using GHK-Cu stimulating wound healing of wound and methods for enhancing wound healing through an animalUS Patent 4,665,054   New glycyl-L-histidyl-L-lysine copper derivatives of...
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Copper - Your Body’s Protective and Anti-Aging Metal

skinbiologywebmaster ·
If you rely on popular articles and health guidelines to provide you with health-relevant information – beware! Often it takes years before scientific research data make their way through bureaucratic hurdles and become available to general public. This is why, despite abundant scientific evidence, copper, an absolutely essential element, is often considered not important and even dangerous. As a result, many people have no idea that they can be at risk of copper deficiency which may put...
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Copper Deficiency

skinbiologywebmaster ·
The majority of data about the symptoms of severe copper deficiency came from animal studies, studies in malnourished children or a rare genetic abnormality - Menkel syndrome. Recently, scientists began to pay attention to signs and consequences of marginal copper deficiency as well. The main sign of severe copper deficiency in animals and humans is anemia that is unresponsive to iron therapy and is accompanied by severe abnormalities in bone marrow. Other symptoms include low white cell...
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Re: IMPORTANT NEWS! GHK-Cu Study on Acute Lung Injury

Ilia ·
good news. Dr Pickart mentioned that some firm plan to make CHK-CU in capsules/tablets, is this work going on?
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Re: IMPORTANT NEWS! GHK-Cu Study on Acute Lung Injury

Dr. Loren Pickart ·
We are very busy writing a book on GHK and its actions. This takes all of our time. I hope some group develops the use of GHK-copper for COPD. The recent paper 2016 indicates that GHK-copper should be able to help damaged lungs.
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Re: DMSO & GHK: A Success Story

Winterskiss ·
Hi I wonder is it ok to add a touch of DMSO to a jar of skin cream that is organic and filled with nourishment so that it would go deeper into the skin for better results ? I have some DMSO 99% unopened still .
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Re: DMSO & GHK: A Success Story

Dr. Loren Pickart ·
DMSO is added to many GHK products. But you only need a little, such as 1 to 2% if you add it yourself.
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Re: Reversal of Emphysema-Related Lung Destruction?

Dr. Loren Pickart ·
There are new reports of lung protection by GHK. 1. . 2016 Sep 6; 7(36): 58405–58417. Published online 2016 Aug 10. doi: 10.18632/oncotarget.11168 PMCID: PMC5295439 The tri-peptide GHK-Cu complex ameliorates lipopolysaccharide-induced acute lung injury in mice Jeong-Ran Park,1,2 Hanbyeol Lee,1 Seok-In Kim,3 and Se-Ran Yang1Oncotarget The tripeptide-copper complex glycyl-l-histidyl-l-lysine-Cu (II) (GHK-Cu) is involved in wound healing and tissue remodeling. Although GHK-Cu exhibits...
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Re: DMSO & GHK: A Success Story

Winterskiss ·
Wow that is awesome !
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Re: DMSO & GHK: A Success Story

Winterskiss ·
Hi Dr . Pickart , why do you say Crepey Skin Escape is not meant to be used around the eye area ? I read this statement but you don't say why . Is it because it contains DMSO ?
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Re: DMSO & GHK: A Success Story

Dr. Loren Pickart ·
I don't think it will cause any problems. We just are somewhat over-cautious on newer products. Crepey Skin Escape is receiving great reviews. As for DMSO, I still have not found any real evidence for toxicities. Mechanics have used it for many decades to remove grease from auto parts.
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Re: DMSO & GHK: A Success Story

Winterskiss ·
Thank you Dr . Pickart , I intend to use it on my face as well as my neck and decollete when my order arrives .
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Re: ANNOUNCEMENT: New Article Published on GHK & Nerve Function - A Must Read

Jaconey ·
thanks a lot for this announcement! I think it is rather important to know!
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Re: GHK & Wound Healing: Built-In Natural Regulator of Dermal Repair

Indhupriya ·
It is a very interesting review. We have developed a computational platform ( www.persistent.com/eskin ) for skin research, wherein skin associated pathways like Keratinocyte Differentiation, Wound Healing, Cornification are built. The role of TGF-beta in wound healing is well studied and accommodated in our pathways. It will be valuable to incorporate this information in our pathway models.
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Re: GHK & Wound Healing: Built-In Natural Regulator of Dermal Repair

Skin Biology ·
Dear INDHUPRIYA , Feel free to incorporate any of the GHK data from our research site at: ReverseAgingwithGHK.com - You'll find a wealth of very valuable information that might be of use to you in your pathway models. Data from any of any of Dr. Pickart's Published Articles and Presentations can also be found at: www.skinbiology.com/published-...s-presentations.html Please contact Dr. Pickart directly at: lorenpickart@skinbiology.com with any further questions you may have. Best Wishes, SKIN...
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Re: GHK WITH COPD

Adria Alexis ·
"In the study below, it was found that GHK, at a very low concentration (10 nanomolar) reversed the effects of emphysema on the genes of affected fibroblast cells from the patients." *** *** *** Wow! Is the FDA aware of this? If so, why haven't they approved it and allow it to start being used to help patients? COPD is 24/7 suffering from not being able to get enough oxygen to the brain. A walk to the bathroom becomes a major event. Talking after the slightest exertion is impossible! It is a...
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Re: GHK WITH COPD

Dr. Loren Pickart ·
GHK has a potential for treating several diseases and in all the research on the molecule, no negative actions have ever been reported. But I doubt if it will ever used in the USA because of its low cost. Think of the new $1,000 a day drug for the treatment of hepatitis C of the liver. The best possibility is that it be used as a nutritional supplement and encapsulated in liposomes for oral use. It should fit the legal definition of a nutritional supplement. But GHK may be used in countries...
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Re: GHK WITH COPD

Adria Alexis ·
Originally Posted by Dr. Loren Pickart: I think at times that they want all of us to die in pain, misery, and poverty. Sad to say, but I think you are absolutely right
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