Novel Therapeutics for Emphysema We have followed with great interest recent data on gene expression signature of emphysema-related lung destruction and its reversal by the tripeptide GHK - Genome Medicine CLICK HERE Excerpt: "As the CMap examined the effect of GHK in cancer cell lines, we next sought to verify the effect of GHK treatment in a cell type more relevant to emphysema pathogenesis. We utilized human lung fibroblasts because fibroblasts are the major interstitial cell within the...

Oncotarget. 2016 Aug 10 . doi: 10.18632/oncotarget.11168. [Epub ahead of print] The tri-peptide GHK -Cu complex ameliorates lipopolysaccharide-induced acute lung injury in mice. Park JR 1, 2 , Lee H 1 , Kim SI 3 , Yang SR 1 . Author information Abstract The tripeptide-copper complex glycyl-l-histidyl-l-lysine-Cu (II) ( GHK -Cu) is involved in wound healing and tissue remodeling. Although GHK -Cu exhibits anti-aging and tissue renewing properties, its roles in acute lung injury (ALI)/acute...

good news. Dr Pickart mentioned that some firm plan to make CHK-CU in capsules/tablets, is this work going on?

We are very busy writing a book on GHK and its actions. This takes all of our time. I hope some group develops the use of GHK-copper for COPD. The recent paper 2016 indicates that GHK-copper should be able to help damaged lungs.

Emphysema-Related Lung Destruction and its Reversal by GHK (Genome Medicine) EXCERPT: "Treatment of human fibroblasts with GHK recapitulated TGFβ-induced gene-expression patterns, led to the organization of the actin cytoskeleton, and elevated the expression of integrin β1. Furthermore, addition of GHK or TGFβ restored collagen I contraction and remodeling by fibroblasts derived from COPD lungs compared to fibroblasts from former smokers without COPD... Furthermore, [it was shown] that by...

There are new reports of lung protection by GHK. 1. . 2016 Sep 6; 7(36): 58405–58417. Published online 2016 Aug 10. doi: 10.18632/oncotarget.11168 PMCID: PMC5295439 The tri-peptide GHK-Cu complex ameliorates lipopolysaccharide-induced acute lung injury in mice Jeong-Ran Park,1,2 Hanbyeol Lee,1 Seok-In Kim,3 and Se-Ran Yang1Oncotarget The tripeptide-copper complex glycyl-l-histidyl-l-lysine-Cu (II) (GHK-Cu) is involved in wound healing and tissue remodeling. Although GHK-Cu exhibits...