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Tagged With "gene data copd"

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Re: dosing for injections for antiaging

Dr. Loren Pickart ·
I don't know of any side effects at the dosages typically used which are 1 to 7 mgs daily. In one kilogram amounts, GHK-Cu costs about $10 a gram or $0.10 per milligram. But we have been under FDA pressure for years about the copper peptides and can say little. We cannot say what all the other sellers of copper peptides say about the actions of copper peptides. I have been told many times by FDA people that we have too much science. SuperSmart sells a sublingual form of 5 mgs GHK-Cu but,...
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Re: Copper Misconceptions

Jessica ·
Dear Beth, Many of our clients have emailed us with concerns about the safety of copper. Excessive copper has been blamed for many diseases – Alzheimer's, heart disease, cancer, etc. The problem is that most of this comes from data on blood plasma copper and diseases. But usually, high blood plasma copper is associated with low tissue copper. Most plasma copper (60%) is locked in proteins such as in ceruloplasmin - an acute phase reactant that rises with stress and disease, and other...
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Re: GHK WITH COPD

Adria Alexis ·
"In the study below, it was found that GHK, at a very low concentration (10 nanomolar) reversed the effects of emphysema on the genes of affected fibroblast cells from the patients." *** *** *** Wow! Is the FDA aware of this? If so, why haven't they approved it and allow it to start being used to help patients? COPD is 24/7 suffering from not being able to get enough oxygen to the brain. A walk to the bathroom becomes a major event. Talking after the slightest exertion is impossible! It is a...
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Re: GHK WITH COPD

Kerry ·
My brother just had two heart attacks. After being brought back from the dead twice he found out, during a checkup, that he also has COPD. Like your mom, he is steadily in decline, probably more emotionally and psychologically b/c he really has no hope from his doctors that there is anything that can be done. I am never surprised but always amazed what the supposedly Health Care System is (not) doing for the health of humanity. We know that a cure for cancer was found and used for stage 4...
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Re: GHK WITH COPD

Dr. Loren Pickart ·
This information is for the use of medical researchers and persons interested in health sciences. It must be emphasized that GHK and other copper binding peptides have not been tested on human emphysema and COPD and are not approved for such uses. One way that may help with COPD is to take 6 mg/day of copper glycinate after a meal. Look at the new revision of http://www.skinbiology.com/cop...sema-copd-genes.html . for the reasons behind this idea. It may not stop COPD but it may help to...
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Re: GHK WITH COPD

TheAnswer ·
Google search: Research Peptides ghk 4th in line on the search Do your own research... be your own advocate... in a cool mist is how I would research it for COPD
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Re: GHK WITH COPD

Mike Smalling ·
Dr. Pickart, My name is Mike Smalling, and I’m currently a grad student at Louisiana Tech University studying in molecular science. I have read many of your papers, and became very interested in the tripeptide GHK through them. I have also read Dr. Campbell’s work on COPD, and Dr. Lane’s work with SPARC as well as others. I intended to do a master’s thesis on research of the tripeptide, but after I had gotten through the initial research, my advisors here realized I was in an area they were...
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Re: IMPORTANT NEWS! GHK-Cu Study on Acute Lung Injury

Dr. Loren Pickart ·
We are very busy writing a book on GHK and its actions. This takes all of our time. I hope some group develops the use of GHK-copper for COPD. The recent paper 2016 indicates that GHK-copper should be able to help damaged lungs.
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Re: Reversal of Emphysema-Related Lung Destruction?

Dr. Loren Pickart ·
There are new reports of lung protection by GHK. 1. . 2016 Sep 6; 7(36): 58405–58417. Published online 2016 Aug 10. doi: 10.18632/oncotarget.11168 PMCID: PMC5295439 The tri-peptide GHK-Cu complex ameliorates lipopolysaccharide-induced acute lung injury in mice Jeong-Ran Park,1,2 Hanbyeol Lee,1 Seok-In Kim,3 and Se-Ran Yang1Oncotarget The tripeptide-copper complex glycyl-l-histidyl-l-lysine-Cu (II) (GHK-Cu) is involved in wound healing and tissue remodeling. Although GHK-Cu exhibits...
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Re: Effect on GHK/Cooper Peptides on PGD2 / PGE2

Jessica ·
Dear Seuxin, Our available data of human genes affected by GHK does not include these prostaglandin genes, unfortunately. However, GHK-Copper does stimulate hair growth in animals and humans. You may find more information at www.folligen.com or www.skinbiology.com . In fact, you may find this particular page quite interesting: http://skinbiology.com/copper-...-of-hair-growth.html . If you scroll down a bit you will find a photo of a mouse with impressive hair growth after being treated with...
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Copper - Your Body’s Protective and Anti-Aging Metal

skinbiologywebmaster ·
If you rely on popular articles and health guidelines to provide you with health-relevant information – beware! Often it takes years before scientific research data make their way through bureaucratic hurdles and become available to general public. This is why, despite abundant scientific evidence, copper, an absolutely essential element, is often considered not important and even dangerous. As a result, many people have no idea that they can be at risk of copper deficiency which may put...
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Copper Deficiency

skinbiologywebmaster ·
The majority of data about the symptoms of severe copper deficiency came from animal studies, studies in malnourished children or a rare genetic abnormality - Menkel syndrome. Recently, scientists began to pay attention to signs and consequences of marginal copper deficiency as well. The main sign of severe copper deficiency in animals and humans is anemia that is unresponsive to iron therapy and is accompanied by severe abnormalities in bone marrow. Other symptoms include low white cell...
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GHK & DNA & You

skinbiologywebmaster ·
Dr. Pickart asked me to post this to the forums. Please read and enjoy. Got questions about this musing? Ask and Dr. Pickart will answer it. This information is for the use of medical researchers and persons interested in health sciences. It must be...
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GHK WITH COPD

skinbiologywebmaster ·
This information is for the use of medical researchers and persons interested in health sciences. It must be emphasized that GHK and other copper binding peptides have not been tested on human emphysema and COPD and are not approved for such...
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What are Copper Peptides?

skinbiologywebmaster ·
Copper peptides are the combination of small amino acid chains with copper 2+ (blue copper). Dr. Pickart's entire career focused on the question of why blood from young persons (20-25) supported cells and tissues better blood from older persons...
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GHK induces protective antioxidant protein from Gene SPRR2C

skinbiologywebmaster ·
Ultraviolet radiation increases skin damage by generating Reactive Oxygen Species (ROS) and Reactive Carbonyl Species (RCS). The Broad Institute Gene Pattern found GHK to increase the activity of the SRRR2C human gene 8.2-fold. It produces a small,...
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GHK induces genes that activate the protective Ubiquitin/Proteasome system

skinbiologywebmaster ·
The Ubiquitin/Proteasome system removes damaged proteins from cells. If these damaged proteins are not adequately removed, the cell cannot function properly. This system is also critical for the repair of damaged DNA after ultraviolet radiation...
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GHK Anti-Pain (Analgesic)

skinbiologywebmaster ·
GHK- Anti-Pain (Analgesic) and Anti-Anxiety (Anxiolytic) Actions 1. Opiate peptides help with wound healing and pain control. This appears to be mediated through the opioid mu1 recpetors. 2. GHK possesses both wound healing and anti-pain activities. Based on Broad Institute data, GHK increases expression of the opioid mu1 gene OPRM1 by 13.9 fold. It also increases gene expression of the cannabinoid pain-reducing gene CNR1 by 2.7 fold (average of +3.1 and +2.3). 3. This anti-pain and wound...
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NEW Navigation Bar - Highlights 17 Effects of GHK

Skin Biology ·
Dear Researchers & Visitors: You'll be happy to know that we have a NEW navigation bar that will facilitate your search for copper peptide studies and effects. This navigation box will be able to be found on the right hand side of our science sites . We are working on slowly dispersing this box so that it is easy to locate on whatever page you are navigating. Why is this so important? In one single area, you'll be able to see an overview of numerous important skin and...
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COPD and GHK

Kerry ·
Greetings! I have just read where you have stated that GHK has been found to improve COPD (chronic obstruction pulmonary disease) conditions. Exactly how does the GHK work with a lung disease. My brother has COPD and he seems to be in a slow but...
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Over 30% of Human Genes Affected by GHK-Cu? YES

Skin Biology ·
The Broad Institute in Boston (managed by Harvard and MIT) analyzes the effect of molecules on human genes to predict the most effective method for the treatment of diseases. Their Connectivity Map is a large database that contains more than...
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GHK and DNA: Resetting the Human Genome to Health

skinbiologywebmaster ·
Abstract: During human aging there is an increase in the activity of inflammatory, cancer promoting, and tissue destructive genes plus a decrease in the activity of regenerative and reparative genes. The human blood tripeptide GHK possesses many positive effects but declines with age. It improves wound healing and tissue regeneration (skin, hair follicles, stomach and intestinal linings, and boney tissue), increases collagen and glycosaminoglycans, stimulates synthesis of decorin, increases...
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Approved for Publication! NEW Review Article on GHK & Skin Regeneration

Skin Biology ·
Approved for Publication! NEW Review Article on GHK & Skin Regeneration Dr. Loren Pickart's latest review article has been approved for publication and was released in the April 2015 edition of BioMed Research International [this publication focuses on research articles in multiple areas of life sciences and was formerly known as Journal of Biomedicine and Biotechnology ]. Here is a brief excerpt of what you can expect to learn when you download your free copy : GHK Peptide as a Natural...
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NEW ARTICLE: Power of GHK-Cu on Modifying Gene Expression

Skin Biology ·
GHK-Cu May Prevent Oxidative Stress in Skin by Regulating Copper and Modifying Expression of Numerous Antioxidant Genes Loren Pickart , Jessica Michelle Vasquez-Soltero and Anna Margolina Accepted: 21 July 2015 | Published: 28 July 2015 ABSTRACT: The copper binding tripeptide GHK (glycyl-l-histidyl-l-lysine) is a naturally occurring plasma peptide that significantly declines during human aging. It has been established that GHK:Copper(2+) improves wound healing and tissue regeneration and...
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Biological Similarities of GHK-Copper: How It May Affect You

Skin Biology ·
Biological Similarities of GHK-Copper: How It May Affect You GHK has many diverse biological actions, an effect which unfortunately makes acceptance of its biological role by many researchers difficult. However, there is another copper-binding molecule with surprisingly similar actions to GHK-Copper. The late John R. J. Sorenson (University of Arkansas) developed many salicylate-copper complexes that possess potentially therapeutic actions. The most active of these was...
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One Stop Site for Anti-Aging Effects of GHK

Skin Biology ·
GHK & DNA: Tuning the Piano Keys of Your Genes to Health - Effects on Anti-Aging If looking younger is your New Year's Resolution, the science of GHK-Copper Peptides may hold the key! On aged human skin, GHK's effect has been confirmed to: • Revert skin to younger morphology (in vivo mammalian data) • Increase numerous repair and remodeling genes (in gene expression data) See new chart at: www.reverseagingwithghk.com Discover more at: ReverseAgingwithGHK.com
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GHK & DNA: Tuning the Piano Keys of Your Genes to Health

Skin Biology ·
NEW Interactive Table Redefines What Is Known About GHK GHK’s effect on cellular systems and health problems associated with human aging spans much more than what has been previously thought! Important information has now been compiled on the first comprehensive website outlining the latest knowledge, research, and theoretical practices including GHK-Cu. Visit: www.reverseagingwithghk.com to learn more! CLICK on each topic of interest to discover updated information about GHK's effects on...
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A MUST READ: NEW! Data of the Cosmeceutical and TriPeptide GHK

Skin Biology ·
NEW! Data of the Cosmeceutical and TriPeptide GHK The following paper was just released for public reading - S OFW International Journal for Applied Science - CLICK HERE Excerpt: "The term cosmeceutical refers to the combination of cosmetics and pharmaceuticals and is used to describe cosmetic products with ingredients the are biologically active and have medicinal benefits. The quality of these derma-cosmetics has to be ensured by scientifically well-documented in vivo and in vitro tests...
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GHK's Role in Novel Therapeutics for Emphysema

Skin Biology ·
Novel Therapeutics for Emphysema We have followed with great interest recent data on gene expression signature of emphysema-related lung destruction and its reversal by the tripeptide GHK - Genome Medicine CLICK HERE Excerpt: "As the CMap examined the effect of GHK in cancer cell lines, we next sought to verify the effect of GHK treatment in a cell type more relevant to emphysema pathogenesis. We utilized human lung fibroblasts because fibroblasts are the major interstitial cell within the...
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Why It Should Matter to You: GHK Reverses Cortisone Inhibition of Regeneration

Skin Biology ·
GHK Reverses Cortisone Inhibition of Regeneration - Why It Should Matter to You NEW PAGE! - CLICK HERE: www.reverseagingwithghk.com/ghk-reverses-cortisone-inhibition-of-regeneration.html Cortisone and cortisol are linked to brain problems and dementia. These two very similar molecules are easily converted from one to another.Patients with Alzheimer’s disease have elevated levels of cortisol in their blood streams, compared to healthy patients. This elevation correlated with the degree of...
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Prevent Oxidative Stress in Skin by Regulating Copper?

Skin Biology ·
Could it be Possible to Prevent Oxidative Stress in Skin by Regulating Copper? The copper binding tripeptide GHK (glycyl-l-histidyl-l-lysine) is a naturally occurring plasma peptide that significantly declines during human aging. It has been established that GHK:Copper(2+) improves wound healing and tissue regeneration and stimulates collagen and decorin production. GHK-Cu also supports angiogenesis and nerve outgrowth, improves the condition of aging skin and hair, and possesses antioxidant...
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Looking for validation of our software, eSkIN: Computational platform for skin research

Indhupriya ·
Hi, I am a researcher working in the Systems Biology group at Persistent Systems. We have developed a comprehensive computational platform for skin research, eSkIN. It is aimed at deriving actionable insights from big biological data generated from high-throughput experiments thus completing the “golden triad” of experiment, computation and knowledge. We are looking for skin researchers to validate our software. About eSkIN: eSkIN allows the translation of large scale high-throughput...
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IMPORTANT NEWS! GHK-Cu Study on Acute Lung Injury

Skin Biology ·
Oncotarget. 2016 Aug 10 . doi: 10.18632/oncotarget.11168. [Epub ahead of print] The tri-peptide GHK -Cu complex ameliorates lipopolysaccharide-induced acute lung injury in mice. Park JR 1, 2 , Lee H 1 , Kim SI 3 , Yang SR 1 . Author information Abstract The tripeptide-copper complex glycyl-l-histidyl-l-lysine-Cu (II) ( GHK -Cu) is involved in wound healing and tissue remodeling. Although GHK -Cu exhibits anti-aging and tissue renewing properties, its roles in acute lung injury (ALI)/acute...
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GHK - Now Part of Major Reference Textbook on Skin!

Skin Biology ·
Resetting Skin Genome Back to Health Naturally with GHK Textbook of Aging Skin (Reference Book Abstract) The copper-binding tripeptide GHK (glycyl- l -histidyl- l -lysine) is a naturally occurring plasma peptide widely used in skin care products. It is especially popular in antiaging cosmetic formulations due to its various and well-established positive biological effects on aging skin. It has been established that GHK-Cu improves wound healing and tissue regeneration and stimulates collagen...
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Visual Presentation of Cancer Metastasis Genetic Data

Skin Biology ·
Visual Presentation of Cancer Metastasis Genetic Data and GHK VISIT: www.skinbiology.com/wound-healing-society-2011.htm Dr. Loren Pickart presented the following visual at the Society for the Advancement of Wound Care and the Wound Healing Society in Dallas, Texas. The presentation focused on data confirming that GHK may inhibit cancer genes, suggesting a connection between metastatic cancer cells and similar systems utilized in the early stage of wound healing.
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ANNOUNCEMENT: New Article Published on GHK & Nerve Function - A Must Read

Skin Biology ·
The Effect of GHK on Nervous System Function and Cognitive Decline NEW ARTICLE PUBLISHED!! Why is this so important? A ge-related cognitive decline is a common problem for many elderly people, yet its cause is poorly understood. Over 99% of investigational drugs, participating in over 200 clinical trials, failed to receive approval for the treatment of Alzheimer’s disease [ 1 ]. Even the success of a few approved drugs provides only minimal patient improvement. There is a need for new, safe,...
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Genetic Piano Keys? Could GHK Be the Answer to Retuning You Back to Health?

Skin Biology ·
The Piano Key Theory of Human Aging The main cause of human aging appears to be that the genes lose their optimal pattern of UP and DOWN settings (age 20-25). This is like piano keys. When the piano is new, it plays beautiful music, but with time the piano keys lose their proper tuning as the music is imperfect. Likewise, with time human genes lose their youthful settings and the diseases and conditions of aging set in. GHK, which was discovered during biochemical studies of human aging,...
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NEW BOOK RELEASE! and Why It Is Important

Skin Biology ·
NEW RELEASE - Order here: https://www.createspace.com/7352739 GHK-Copper Peptides for Skin and Hair Beauty Why is this publication is important? Includes never-before released data on cancer, COPD, anti-pain, and anti-anxiety effects of GHK. COPPER PEPTIDES RETUNE YOUR GENE PIANO TO HEALTH - However, not all copper peptides improve skin or hair. Learn from the discoverer of regenerative copper peptides, biochemist Dr. Loren Pickart, the secrets that have most recently been revealed about...
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Book Release: How to Get Your Copy

Skin Biology ·
NEW RELEASE - Order here: https://www.createspace.com/7352739 GHK-Copper Peptides for Skin and Hair Beauty Why is this publication is important? Includes never-before released data on cancer, COPD, anti-pain, and anti-anxiety effects of GHK. COPPER PEPTIDES RETUNE YOUR GENE PIANO TO HEALTH - However, not all copper peptides improve skin or hair. Learn from the discoverer of regenerative copper peptides, biochemist Dr. Loren Pickart, the secrets that have most recently been revealed about...
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It's FINISHED! Why My New Book is My Proud Accomplishment

Skin Biology ·
NEW RELEASE - Order here: https://www.createspace.com/7352739 GHK-Copper Peptides for Skin and Hair Beauty Why is this publication is important? Includes never-before released data on cancer, COPD, anti-pain, and anti-anxiety effects of GHK. COPPER PEPTIDES RETUNE YOUR GENE PIANO TO HEALTH - However, not all copper peptides improve skin or hair. Learn from the discoverer of regenerative copper peptides, biochemist Dr. Loren Pickart, the secrets that have most recently been revealed about...
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NEW Book on Cancer Research and Gene Data

Skin Biology ·
NEW RELEASE - Order here: https://www.createspace.com/7352739 GHK-Copper Peptides for Skin and Hair Beauty Why is this publication is important? Includes never-before released data on cancer, COPD, anti-pain, and anti-anxiety effects of GHK. COPPER PEPTIDES RETUNE YOUR GENE PIANO TO HEALTH - However, not all copper peptides improve skin or hair. Learn from the discoverer of regenerative copper peptides, biochemist Dr. Loren Pickart, the secrets that have most recently been revealed about...
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Reversal of Emphysema-Related Lung Destruction?

Skin Biology ·
Emphysema-Related Lung Destruction and its Reversal by GHK (Genome Medicine) EXCERPT: "Treatment of human fibroblasts with GHK recapitulated TGFβ-induced gene-expression patterns, led to the organization of the actin cytoskeleton, and elevated the expression of integrin β1. Furthermore, addition of GHK or TGFβ restored collagen I contraction and remodeling by fibroblasts derived from COPD lungs compared to fibroblasts from former smokers without COPD... Furthermore, [it was shown] that by...
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NEW RELEASE: Actions of GHK in the Light of New Gene Data

Skin Biology ·
Protective Actions of GHK-Cu Peptide in the Light of NEW Gene Data (International Journal of Molecular Sciences - July 2018) The following paper was just released for public viewing: Dr. Pickart's NEW Article on Protective Actions of GHK-Cu Peptide - CLICK HERE Excerpt: " The human peptide GHK (glycyl- l -histidyl- l -lysine) has multiple biological actions, all of which, according to our current knowledge, appear to be health positive. It stimulates blood vessel and nerve outgrowth,...
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Why Following GHK-Cu Research Is VITAL

Skin Biology ·
Diseases of aging affect us all - B ased on laboratory data and gene profiling data, GHK-Cu may be used to improve stem cell therapy and to help shift regeneration processes of a number of organs back to healthy regeneration. Keep up-to-date with all of the recent studies, university and lab research, and potential uses of GHK-Cu ( glycine-L-histidine-lysine). Contact us at: ghkcopperpeptides@gmail.com for additional information READ MORE: Published Articles and Presentations - The Science...
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Some general questions especially for the safe use of GHK

Martin Gatmin ·
I've been following the research and a lot of basic papers regarding the possible use of GHK for COPD. I am aware there is no offical study or practical use currently, but since major adverse effects seem to be unlikely and COPD is no fun I came to the decision to give it a try. With the planned use arose some questions to be as safe as possible. Hopefully Dr. Pickard or some experienced users have some advise or answers. 1) GHK / GHK-Cu for injection (vials) is available from many suppliers...
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Longer Telomeres Increase Cancer in Humans

Skin Biology ·
Longer Telomeres Increase Cancer in Humans (Important 22 Year Study) There is an idea that longer telomeres in humans will extend the lifespan. However, the following study of 28,000 people over 22 years found that those with the longest telomeres have much higher rates of cancer - CLICK HERE STUDY DETAILS: For the new study, researchers analyzed blood samples and health data on more than 28,000 Chinese people in the Singapore Chinese Health Study, which has followed the health outcomes of...
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Re: A MUST READ: NEW! Data of the Cosmeceutical and TriPeptide GHK

Indhupriya ·
Is the gene regulation by GHK data available in public repositories?
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Re: A MUST READ: NEW! Data of the Cosmeceutical and TriPeptide GHK

Dr. Loren Pickart ·
All the GHK gene data is available from the Broad Institute in Boston. As we analyze the data we have, we publish our results for others.
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Re: GHK & Wound Healing: Built-In Natural Regulator of Dermal Repair

Skin Biology ·
Dear INDHUPRIYA , Feel free to incorporate any of the GHK data from our research site at: ReverseAgingwithGHK.com - You'll find a wealth of very valuable information that might be of use to you in your pathway models. Data from any of any of Dr. Pickart's Published Articles and Presentations can also be found at: www.skinbiology.com/published-...s-presentations.html Please contact Dr. Pickart directly at: lorenpickart@skinbiology.com with any further questions you may have. Best Wishes, SKIN...
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