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Tagged With "Acetyl Octapeptide-1"

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Re: dosing for injections for antiaging

Dr. Loren Pickart ·
Hi Dr. Pickart, I've been using GHK-Cu for 4 weeks at 5mg daily. I've had great effects including skin, cognitive function and hair growth, it's pretty incredible! I have a quick question that I'm hoping you can answer. You recommend the purchase of GHK-Cu through Ceretropic. I'm curious what dose people use for anti aging effects. I'm concerned of copper toxicity and taking to much of GHK-Cu. I've spoken with you on the phone and had a great conversation with you! You're done amazing work...
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Re: dosing for injections for antiaging

Dr. Loren Pickart ·
I don't know of any side effects at the dosages typically used which are 1 to 7 mgs daily. In one kilogram amounts, GHK-Cu costs about $10 a gram or $0.10 per milligram. But we have been under FDA pressure for years about the copper peptides and can say little. We cannot say what all the other sellers of copper peptides say about the actions of copper peptides. I have been told many times by FDA people that we have too much science. SuperSmart sells a sublingual form of 5 mgs GHK-Cu but,...
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Re: dosing for injections for antiaging

Lois R ·
I have a Peptide Sciences vial of GHK-cu 200 mg. How much bacteriostatic water should I use to reconstitute it. I want to give daily doses of 1 mg. Thank you. VERY MUCH.
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Re: dosing for injections for antiaging

Lois R ·
I am needing reconstitution rates. I have purchased a vial of Peptide Science GHK-cu 200 mg. How much bacteriostatic water do I use? I want to be able to give daily doses of 1 mg. Thank you.
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Re: dosing for injections for antiaging

Adam ·
Hello Dr. Pickart, I’ve been following your work for years with much interest You mention; ”The only issue is to keep copper and zinc in a rough balance of about 5 parts zinc to 1 part copper.” In maintaining proper zinc/copper balance are oral zinc supplements suitable for raising zinc levels? Thank you, Adam
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Re: Copper Misconceptions

Adria Alexis ·
Originally Posted by Kirsten: Can you share which foods are naturally high in copper that we should be incorporating into our diets? According to this article by Dr. Andrew Weil some foods are: How do you get enough copper from foods? Good food sources include vegetables, legumes, beans , nuts and seeds, mushrooms, shellfish (especially cooked oysters), avocado and whole grains. Also too much zinc or iron can lower the copper in your body. Also: Are there any other special considerations?
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Re: Copper Misconceptions

Jessica ·
Dear Beth, Many of our clients have emailed us with concerns about the safety of copper. Excessive copper has been blamed for many diseases – Alzheimer's, heart disease, cancer, etc. The problem is that most of this comes from data on blood plasma copper and diseases. But usually, high blood plasma copper is associated with low tissue copper. Most plasma copper (60%) is locked in proteins such as in ceruloplasmin - an acute phase reactant that rises with stress and disease, and other...
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Re: DMSO & GHK: A Success Story

Dr. Loren Pickart ·
DMSO is added to many GHK products. But you only need a little, such as 1 to 2% if you add it yourself.
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Re: Reversal of Emphysema-Related Lung Destruction?

Dr. Loren Pickart ·
There are new reports of lung protection by GHK. 1. . 2016 Sep 6; 7(36): 58405–58417. Published online 2016 Aug 10. doi: 10.18632/oncotarget.11168 PMCID: PMC5295439 The tri-peptide GHK-Cu complex ameliorates lipopolysaccharide-induced acute lung injury in mice Jeong-Ran Park,1,2 Hanbyeol Lee,1 Seok-In Kim,3 and Se-Ran Yang1Oncotarget The tripeptide-copper complex glycyl-l-histidyl-l-lysine-Cu (II) (GHK-Cu) is involved in wound healing and tissue remodeling. Although GHK-Cu exhibits...
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Re: dosing for injections for antiaging

Dr. Loren Pickart ·
I would not recommend injecting GHK-Cu. We just have little information on human injections. GHK-Cu passes the stratum corneum rather easily, so just using the product on your skin, should put some GHK-Cu into your body. And GHK-Cu works at 1 nanomolar on cells. The Russian anti-anxiety studies in rats found GHK strongly affects the rats within 12 minutes at a dosage that would correspond to 35 micrograms in humans.
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Re: Basal Cell Cancer on Nose

Dr. Loren Pickart ·
Retinoic acid is a drug and cannot be used in cosmetics. We have scar reduction methods at scar-reduction.com but your physician must approve of what you do because of the cancer. Below is one idea - retinoic acid and glycolic acid. Indian Dermatol Online J. 2015 Mar-Apr;6(2):84-8. doi: 10.4103/2229-5178.153007. Retinoic acid and glycolic acid combination in the treatment of acne scars . Chandrashekar BS 1 , Ashwini KR 1 , Vasanth V 1 , Navale S 1 . Author information Abstract INTRODUCTION:...
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Re: Dosing

Skin Biology ·
Dr. Pickart says: "My earlier estimates of the amount of GHK-Cu needed for human effects were far too high. Since we are in the USA, we only have good reports on GHK-Cu working well at 1 to 7 mgs per day by injection. The SuperSmart GHK-Cu has Linguinal 5 mg GHK-Cu and we have a number of good reports on that product. We don't have much information on the GHK-Cu nasal spray which is sold in Europe and the Middle East."
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GHK Suppression of Cancer Metastasis Genes

Jessica ·
This information is for the use of medical researchers and persons interested in health sciences. It must be emphasized that GHK and other copper binding peptides have not been tested on human cancers and are not approved for such uses. In 2010,...
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Wound Healing & Skin Repair Using Copper Peptides

skinbiologywebmaster ·
 StudyResultReference US Patents describing methods using GHK-Cu stimulating wound healing of wound and methods for enhancing wound healing through an animalUS Patent 4,665,054   New glycyl-L-histidyl-L-lysine copper derivatives of...
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Copper Peptide Skin Solution That Works

skinbiologywebmaster ·
Do you feel tired? Frustrated? Desperate? Do you keep spending money on skin care solutions that do not work? Indeed, with so many cosmetic products promising to ban wrinkles, lines and creases, eradicate cellulite and eliminate acne, why do we still have all those skin problems? Why is it that everywhere we look, we still see wrinkles and lines and sagging skin? Well, maybe with the exception of glamorous beauties of Hollywood, but who knows how many surgeries it took to achieve that look.
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Copper Misconceptions

Jessica ·
Quite often, modern scientists toil for decades only to discover something that our ancestors knew all along from observation and keen intuition. Even after the essential discovery is made, it may take years before the official health guidelines catch up with the scientific research. It is because of this that copper, an absolutely essential element for human health, has only recently started to attract the attention of nutrition gurus. Still today, not many people know that they are at risk...
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GHK-Cu In relation to Wound Healing

skinbiologywebmaster ·
Dr. Pickart had me post this for your reading enjoyment. In 1984, I observed that GHK-Cu possesses a mild antioxidant activity similar to the enzyme superoxide dismutase, which manifests itself as a calming of red and irritated skin. Steve Aust’s lab at Utah State University discovered that GHK-Cu blocks the damage-induced release of oxidizing iron molecules from ferritin. Further discoveries followed. Vinci et al. at the University of Catalina in Italy reported that GHK-Cu blocks tissue...
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Application of peptide gly-his-lys for analgesic effect in pain caused by thermal stimulation

skinbiologywebmaster ·
IPC classes: fficial%26channel%3Dsb&rurl=translate.google.com&sl=ru&u=http://www.freepatent.ru/MPK/A/A61/A61K/A61K38/A61K3806&usg=ALkJrhhaheibcAMPOYKoAGZ_zF2YheKOUg" target="_blank">A61K38/06 .. tripeptides fficial%26channel%3Dsb&rurl=translate.google.com&sl=ru&u=http://www.freepatent.ru/MPK/A/A61/A61P/A61P3/A61P302&usg=ALkJrhhbQxB8aTcSnHtl_Y5UdwEC8ggtFQ" target="_blank">A61P3/02 . nutrients such as vitamins, minerals, Author (s): Dolgintsev Maxim E.
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GHK Anti-Pain (Analgesic)

skinbiologywebmaster ·
GHK- Anti-Pain (Analgesic) and Anti-Anxiety (Anxiolytic) Actions 1. Opiate peptides help with wound healing and pain control. This appears to be mediated through the opioid mu1 recpetors. 2. GHK possesses both wound healing and anti-pain activities. Based on Broad Institute data, GHK increases expression of the opioid mu1 gene OPRM1 by 13.9 fold. It also increases gene expression of the cannabinoid pain-reducing gene CNR1 by 2.7 fold (average of +3.1 and +2.3). 3. This anti-pain and wound...
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GHK and Anti-Anxiety

skinbiologywebmaster ·
Anti-Anxiety (Anxiolytic) Use of peptide gly-his-lys for anxiolytic effect. RU patent 2480232.   SUBSTANCE: invention refers to medicine, namely physiology, pathophysiology and pharmacology, and may be used for an anxiolytic (antianxiety) effect....
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GHK-Cu and Graft Healing of ACLR

Skin Biology ·
INTRA-ARTICULAR INJECTION OF TRIPEPTIDE COPPER COMPLEX GHK-CU (II) IMPROVED GRAFT HEALING IN ANTERIOR CRUCIATE LIGAMENT RECONSTRUCTION Sai-Chuen Fu,Yau-Chuk Cheuk, Wai-Hang Cheng, Shu-Hang Yung, Christer G Rolf, Kai-Ming Chan 1 1 Department of Orthopaedics and Traumatology, Faculty of Medicine, Faculty of Medicine, The Chinese University of Hong Kong. Department of Orthopaedic Surgery, Huddinge University Hospital, CLINTEC, Karolinska Institutet, Stockholm, Sweden INTRODUCTION Anterior...
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Actinic Keratosis: GHK Outperforms Other Topicals

Skin Biology ·
Actinic keratosis are gray-to-pink-to-red, scaly spots called actinic keratosis. These usually occur on your face, scalp and the backs of hands. They start as flat lesions that feel like sandpaper, but later may develop a hard, wart-like surface....
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GHK-Cu and Inflammatory Bowel Disease Study

Skin Biology ·
Intestinal and Stomach Healing GHK-Cu has potent effects on the healing of stomach ulcers and intestinal inflammations. One small human study found a very positive effect of GHK-Cu on the healing of intestinal lesions in persons with refractory...
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4 Basic Changes of Aging: How GHK Combats Each of Them

Skin Biology ·
What Happens to Our Skin as We Get Older? There are 4 basic biochemical changes our skin goes through during the aging process:   Change 1:  The rate of the skin cell replacement decreases, producing a thinner, more fragile skin. Skin is...
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mixing GHK-Cu with other skinactives

Zaril ·
I recently purchased a 7% GHK-Cu for a DIY moisturizer mixture. I remember reading that due to stability issues mixing GHK-Cu with AHAs or Vitamin-C is not advised.   I am considering mixing it together with the following actives:   1% CoQ10...
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What Is Skin Remodeling? Can You See It?

Skin Biology ·
SKIN REMODELING  is the process that removes damaged proteins and older cells from the skin thus reducing scars, lesions, and wrinkles while smoothing out skin texture and tone. Increasing skin remodeling is the key to producing biologically...
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Approved for Publication! NEW Review Article on GHK & Skin Regeneration

Skin Biology ·
Approved for Publication! NEW Review Article on GHK & Skin Regeneration Dr. Loren Pickart's latest review article has been approved for publication and was released in the April 2015 edition of BioMed Research International [this publication focuses on research articles in multiple areas of life sciences and was formerly known as Journal of Biomedicine and Biotechnology ]. Here is a brief excerpt of what you can expect to learn when you download your free copy : GHK Peptide as a Natural...
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GHK Proved Similar to NSAIDs - How?

Skin Biology ·
NSAIDs and GHK: Unexpected Similarities! G HK and GHK-Cu may function as the circulating human non-steroidal anti- inflammatories (NSAIDs). In human plasma there is about 200 nanograms per milliliters of GHK and GHK-Cu at age 20. This declines to...
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Rosacea: Endoplasmic reticulum stress(Pandora) and possible effects by GHK/Copper

Ilia ·
Good day! I found good 2016 article from Germany about rosacea cell mechanisms. Dr. Pickart or anybody, do You have any information of correlation of GHK/Copper with endoplasmatic reticulum(as Pandora of rosacea)? any positive regulative effects on ER? I add this article full text.
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IMPORTANT NEWS! GHK-Cu Study on Acute Lung Injury

Skin Biology ·
Oncotarget. 2016 Aug 10 . doi: 10.18632/oncotarget.11168. [Epub ahead of print] The tri-peptide GHK -Cu complex ameliorates lipopolysaccharide-induced acute lung injury in mice. Park JR 1, 2 , Lee H 1 , Kim SI 3 , Yang SR 1 . Author information Abstract The tripeptide-copper complex glycyl-l-histidyl-l-lysine-Cu (II) ( GHK -Cu) is involved in wound healing and tissue remodeling. Although GHK -Cu exhibits anti-aging and tissue renewing properties, its roles in acute lung injury (ALI)/acute...
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GHK - Now Part of Major Reference Textbook on Skin!

Skin Biology ·
Resetting Skin Genome Back to Health Naturally with GHK Textbook of Aging Skin (Reference Book Abstract) The copper-binding tripeptide GHK (glycyl- l -histidyl- l -lysine) is a naturally occurring plasma peptide widely used in skin care products. It is especially popular in antiaging cosmetic formulations due to its various and well-established positive biological effects on aging skin. It has been established that GHK-Cu improves wound healing and tissue regeneration and stimulates collagen...
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ANNOUNCEMENT: New Article Published on GHK & Nerve Function - A Must Read

Skin Biology ·
The Effect of GHK on Nervous System Function and Cognitive Decline NEW ARTICLE PUBLISHED!! Why is this so important? A ge-related cognitive decline is a common problem for many elderly people, yet its cause is poorly understood. Over 99% of investigational drugs, participating in over 200 clinical trials, failed to receive approval for the treatment of Alzheimer’s disease [ 1 ]. Even the success of a few approved drugs provides only minimal patient improvement. There is a need for new, safe,...
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NEW BOOK RELEASE! and Why It Is Important

Skin Biology ·
NEW RELEASE - Order here: https://www.createspace.com/7352739 GHK-Copper Peptides for Skin and Hair Beauty Why is this publication is important? Includes never-before released data on cancer, COPD, anti-pain, and anti-anxiety effects of GHK. COPPER PEPTIDES RETUNE YOUR GENE PIANO TO HEALTH - However, not all copper peptides improve skin or hair. Learn from the discoverer of regenerative copper peptides, biochemist Dr. Loren Pickart, the secrets that have most recently been revealed about...
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Book Release: How to Get Your Copy

Skin Biology ·
NEW RELEASE - Order here: https://www.createspace.com/7352739 GHK-Copper Peptides for Skin and Hair Beauty Why is this publication is important? Includes never-before released data on cancer, COPD, anti-pain, and anti-anxiety effects of GHK. COPPER PEPTIDES RETUNE YOUR GENE PIANO TO HEALTH - However, not all copper peptides improve skin or hair. Learn from the discoverer of regenerative copper peptides, biochemist Dr. Loren Pickart, the secrets that have most recently been revealed about...
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It's FINISHED! Why My New Book is My Proud Accomplishment

Skin Biology ·
NEW RELEASE - Order here: https://www.createspace.com/7352739 GHK-Copper Peptides for Skin and Hair Beauty Why is this publication is important? Includes never-before released data on cancer, COPD, anti-pain, and anti-anxiety effects of GHK. COPPER PEPTIDES RETUNE YOUR GENE PIANO TO HEALTH - However, not all copper peptides improve skin or hair. Learn from the discoverer of regenerative copper peptides, biochemist Dr. Loren Pickart, the secrets that have most recently been revealed about...
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NEW Book on Cancer Research and Gene Data

Skin Biology ·
NEW RELEASE - Order here: https://www.createspace.com/7352739 GHK-Copper Peptides for Skin and Hair Beauty Why is this publication is important? Includes never-before released data on cancer, COPD, anti-pain, and anti-anxiety effects of GHK. COPPER PEPTIDES RETUNE YOUR GENE PIANO TO HEALTH - However, not all copper peptides improve skin or hair. Learn from the discoverer of regenerative copper peptides, biochemist Dr. Loren Pickart, the secrets that have most recently been revealed about...
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DMSO & GHK: A Success Story

Skin Biology ·
DMSO & GHK: A Success Story Background & Observations : GHK-Cu improved the skin transplants with the best results being obtained by using GHK-Cu dissolved in a small amount of DMSO (dimethylsulfoxide). Normally in skin grafts, most of the grafted skin dies off, and new skin grows outward from the surviving core of the skin graft. However, the addition of DMSO often so improved the graft "take" that the final graft "take" area exceeded the actual size of the skin graft. Periphery of...
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Anti-Aggression, Anti-Anxiety, Anti-Pain

Dr. Loren Pickart ·
GHK effects: Anti-aggression, Anti-anxiety, Anti-pain Anti-aggression actions Comment. The anti-aggression actions of GHK, if scaled up for a human, would occur at a dosage of about 0.3 mgs. The GHK is produced in Russia at the State University of Saint Petersburg, Putin's school. So the Russians can spray opposing armies with GHK and turn them into 1970s style California flower children. Effects of Tripeptide Gly-His-Lys in Pain-Induced Aggressive-Defensive Behavior in Rats Bulletin of...
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Breaking News: Strokes and GHK's Neuroprotective Effects

Skin Biology ·
Glycine-Histidine-Lysine (GHK) Alleviates Neuronal Apoptosis Due to Intracerebral Hemorrhage via the miR-339-5p/VEGFA Pathway (Frontiers in Neuroscience - September 2018) The following paper was just published this September | Read for yourself and your family: Glycine-Histidine-Lysine (GHK) Alleviates Neuronal Apoptosis Due to Intracerebral Hemorrhage via the miR-339-5p/VEGFA Pathway Excerpt: " Although it accounts for approximately 15% of all stroke cases, hemorrhagic stroke is associated...
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RUSSIAN Articles: Biological Mechanism of Action of GHK-Cu TriPeptide

Skin Biology ·
The primary cause of human aging and its attendant diseases are changes in the activity of the human genome. During aging there is an increase in the activity of inflammatory, cancer promoting, and tissue destructive genes plus a decrease in the activity of regenerative and reparative genes. Regenerative copper peptides appear to help maintain wellness and youth. The human peptide GHK induces a plethora of health associated actions such as tissue repair, anti-inflammatory actions,...
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(Russian Articles) - Is GHK the Secret to Unlock Human Aging?

Skin Biology ·
The primary cause of human aging and its attendant diseases are changes in the activity of the human genome. During aging there is an increase in the activity of inflammatory, cancer promoting, and tissue destructive genes plus a decrease in the activity of regenerative and reparative genes. Regenerative copper peptides appear to help maintain wellness and youth. The human peptide GHK induces a plethora of health associated actions such as tissue repair, anti-inflammatory actions,...
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Does Magnesium Citrate interfer with Copper Absorption?

Rossana ·
I would like to ask Skin Biology an opinion about Magnesium Citrate supplements. I have been taking Magnesium Citrate powder for years. It is the only magnesium form that I know of that is tasteless and I prefer powders to pills. I typically sprinkle 1 teaspoon of magnesium citrate on a meal, once or twice a day. 1 tsp = 3325 mg Magnesium Citrate = 540 mg elemental Magnesium. I recently read some references that magnesium, in the form of magnesium citrate, interferes with copper absorption...
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Some general questions especially for the safe use of GHK

Martin Gatmin ·
I've been following the research and a lot of basic papers regarding the possible use of GHK for COPD. I am aware there is no offical study or practical use currently, but since major adverse effects seem to be unlikely and COPD is no fun I came to the decision to give it a try. With the planned use arose some questions to be as safe as possible. Hopefully Dr. Pickard or some experienced users have some advise or answers. 1) GHK / GHK-Cu for injection (vials) is available from many suppliers...
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Acetyl Hexapeptide-8

youngshe2015 ·
Acetyl Hexapeptide-3, Acetyl Hexapeptide-8 L 9.21 1.Basic information: INCI Name: Acetyl Hexapeptide-3, Acetyl Hexapeptide-8 Reference: Argireline Cas No: 616204-22-9 Formula: C34H60N14O12S Molecular:887 Sequence: Ac-Glu-Glu-Met-Gln-Arg-Arg-NH2 Purity: ≧95% Source: synthetic Grade: cosmetic Stability: stable Solubility: soluble in water Odor: no Formulation: available for your reference, please contact us. MSDS and COA: available for your reference, please contact us. Delivery: promptly from...
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Cosmetic Peptides Knowledge Popularization--Myristoyl hexapeptide-16

Bella-Youngshe ·
Myristoyl hexapeptide-16 INCI: Myristoyl hexapeptide-16 What is Myristoyl hexapeptide-16? Myristoyl hexapeptide-16 is a synthetic compound produced by a reaction between Myristic acid and hexapeptide-16. It is a synthetic fatty acid linked with a long chain of polypeptides. Peptides are long chains of amino acids, the building material of proteins. It comes as colorless to pale beige clear liquid with a faint odor. Use & Benefits: Myristoyl hexapeptide-16 is categorized as protein...
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cosmetics skin care human oligopeptide - 1 sh-oligopeptide-1 bioeffect egf oligopeptide

Bella-Youngshe ·
Recombinant human epidermal growth factor (EGF) 1.Basic Information: Name: EGF,Recombinant human epidermal growth factor (rhEGF) CAS No.: 62253-63-8Grade: cosmetic INCI Name: Human Oligopeptide-1 Endotoxin level: less than 0.1 ng per μg (1EU/ug). 2.Introduction: EGF secreted by each of us, when we were in child times the secretion is the highest, and then it decreased with age increases. Particularly, After 22 years of age, reduced secretion was more pronounced. When we use cosmetics...
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Sh-Oligopeptide-4 Thymosin Beta-4 TB500 Thymosin Beta-4

Bella-Youngshe ·
1.Basic information: Name: Thymosin Beta-4 Reference: Sh-Oligopeptide-4, TB500 Sequence:Ac-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln-Glu-Lys-Asn-Pro-Leu-Pro-Ser-Lys-Glu-Thr-Ile-Glu-Gln-Glu-Lys-Gln-Ala-Gly-Glu-Ser Molecular formula: C212H350N56O78S Molar Mass: 4963.4408 CAS number: 77591-33-4 Purity: 98% Source: synthetic Grade: cosmetic Capacity: 300g per month Appearance: white powder 2.Fuction: • Endothelial (blood vessels) cell...
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Biotinoyl tripeptide-1 powder/solution CAS 299157-54-3

Bella-Youngshe ·
Product Name Biotinoyl tripeptide-1 powder/solution CAS 299157-54-3 Appearance white powder/solution CAS 299157-54-3 MF C24H38N8O6S MW N/A Purity 99% Application Cosmetic Products Storage Keep in cool & dry place,stay away from strong light and heat Shelf Life 24 months What is Tripeptide-1? Tripeptide-1 has many positive effects on cells. It can effectively inhibit cell degeneration, enhance immune function, reduce collagen loss, thus improving relaxation; Help damaged cells repair, improve...
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Recombinant human epidermal growth factor (rhEGF)

Bella-Youngshe ·
Recombinant human epidermal growth factor (rhEGF) 1.Basic Information: Name: EGF,Recombinant human epidermal growth factor (rhEGF) CAS No.: 62253-63-8 Grade: cosmetic INCI Name: Human Oligopeptide-1 Endotoxin level: less than 0.1 ng per μg (1EU/ug). 2.Introduction: EGF secreted by each of us, when we were in child times the secretion is the highest, and then it decreased with age increases. Particularly, After 22 years of age, reduced secretion was more pronounced. When we use cosmetics...
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High Purity Cosmetic Grade Copper Peptide GHK-CU

Bella-Youngshe ·
Product name : Copper Peptide GHK-CU Other Name: GHK-CU Purity:98%min Grade : cosmetic grade Recommend dosa: 0.2% for external use Main benefits: Antioxidant, stimulates collagen production,Skin care, anti-aging Who should use it: In general, anyone looking to get rid of aging. GHK-CU Description Copper peptides have been clinically shown to offer a wide variety of benefits for the skin and hair. Often, the complexes are used in skin care lotions, creams and serums designed to reduce the...
 
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