Copper peptides are the combination of small amino acid chains with copper 2+ (blue copper). Dr. Pickart's entire career focused on the question of why blood from young persons (20-25) supported cells and tissues better blood from older persons (60-80).
During this work, he isolated the copper binding tripeptide GHK (Gly-His-Lys) which appeared to be the major reason for the superiority of young blood.
For skin health, a variety of copper peptides are able to transfer nutritional copper into the skin. GHK-copper works well on skin but Pickart has found other copper peptides that are more effective.
GHK's unique chemistry only becomes important within the human body. There is a fierce competition for copper 2+ and GHK has the exact binding affinity to transfer copper in and our of cells and tissue.
Almost, all other peptides cannot compete for copper 2+ in the body. However, there are very low levels of GHK in the body and the small amount of copper it transfers must trigger a special system that controls or strongly affects about 3,600 human genes or 16% of the human genome.
We are currently analyzing genome and biochemical data to understand the function of GHK in humans. The primary cause of aging and disease is a silencing of active genes as we age but these dormant genes can be turned on under the right stimulus. GHK may act to "set" "or "reset" the youthful gene pattern.